Metabolic engineering in the post-genomic era is characterised by the development of new methods for metabolomics and fluxomics. supported by the integration of genetic engineering tools and mathematical modelling. Particularly. constraint-based stoichiometric models have been widely studied: (i) flux balance analysis (FBA) (in silico). https://www.ofertastrailrunning.com/product-category/shabby-chic-art/